"Scientists have linked the genetic modifications associated with flight with beneficial modifications to the bat’s immune system. For example, the bat’s immune system fights viral infections but does not overreact to them, preventing bats from falling ill from the many viruses they have
According to new research, it's because bats may be the ultimate incubator, courtesy of a fiercely effective and robust immune system that seems to, in effect, train up viral strains, encouraging them to adapt and evolve into becoming as fit and infectious as they possibly can.
The African green monkey cell line does not possess such advantages. In experiments, when the cell cultures were exposed to viruses mimicking Ebola and Marburg virus, the monkey cells were quickly overwhelmed. The bat cells, on the other hand, resisted the viral onslaught, thanks to their rapid interferon signalling.
The paradox, though, is that interferon ultimately seems to benefit viruses, even while it hinders their capacity to kill cells. While the signalling system prevents cells from dying, the infection nonetheless holds on, and the virus starts to adapt to the defensive regime, at least according to the team's computer simulations.
This suggests that having a really robust interferon system would help these viruses persist within the host," says biologist and first author of the study, Cara Brook.
However, researchers have found that when bats contract these viruses, their particularly strong immune systems prevent them from getting sick or dying from the infections. This means they can continue to carry and pass on the virus, whereas other animals that contract it may get sick and die, and therefore are less likely to pass it on. The UC Berkeley researchers found that a bat’s immune system is so strong, in fact, that when a virus infects a bat, the animal’s immune system response is thought to cause the virus to adapt and replicate even faster. That means when the virus infects an animal with a weaker immune system (let’s say a human), the virus is able to wreak havoc.
One of the reasons bats have such strong immune systems is thought to be the fact that they can fly, according to the UC Berkeley study. When they fly, bats elevate their metabolic rates to a level that would hurt other mammals, but for bats, helped them develop an immune system that is able to quickly repair the cell damage caused by flight, the researchers found."
Yarasa-covid19 mevzusuyla ilgili 1-2 makaledeki ilgili satırları birleştirdim.
Lavuklar virüsü bir de upgradeleyip veriyorlar bize. Bu bela biterse şu yarasaların bağışıklık sistemi üzerine eğilmek lazım. Hem de memeliler. İğrenç hayvanlar olmalarından ziyade virüslere karşı dayanıklı olmalarından kaynaklanıyor sars-covid vsnin bunlardan çıkması. Doğal ev sahipliğini yaptıkları corona bize bulaşınca öldürüyor. Tabii direkt yarasadaki halini almıyoruz yarasandan, pangoline oradaki mutasyonla insana.